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Enzymatic formation of 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid: kinetics of the reaction and stereochemistry of the product

✍ Scribed by Jesper Haeggström; Anders Wetterholm; Mats Hamberg; Johan Meijer; Robert Zipkin; Olof Rådmark


Book ID
115740059
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
721 KB
Volume
958
Category
Article
ISSN
0005-2760

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The preparation of a 11C-labelled 5-lipo
✍ Franz Oberdorfer; Thilo Siegel; Albrecht Guhlmann; Dietrich Keppler; Wolfgang Ma 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 451 KB

## Abstract 5(S)‐Hydroxy‐6(R)‐(N‐[1‐^11^C]acetyl)cysteinyl‐7,9‐trans‐11,14‐cis‐eicosatetraenoic acid (N‐[1‐^11^C]acetyl leukotriene E~4~) was prepared by the reaction of leukotriene E~4~ and [1‐^11^C]acetyl chloride. The product was obtained with 1.3% yield, based on [1‐^11^C]acetyl chloride. The p