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Enzymatic Characterization and Inhibitor Discovery of a New Cystathionine -Synthase from Helicobacter pylori

โœ Scribed by Kong, Y.; Wu, D.; Bai, H.; Han, C.; Chen, J.; Chen, L.; Hu, L.; Jiang, H.; Shen, X.


Book ID
126694186
Publisher
Oxford University Press
Year
2007
Tongue
English
Weight
589 KB
Volume
143
Category
Article
ISSN
0021-924X

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## Abstract Thymidylate synthase X (ThyX) catalyzes the methylation of dUMP to form dTMP in bacterial life cycle and is regarded as a promising target for antibiotics discovery. __Helicobacter pylori__ is a human pathogen associated with a number of human diseases. Here, we cloned and purified the