Environmental photodegradation of mefenamic acid
β Scribed by Jeffrey J. Werner; Kristopher McNeill; William A. Arnold
- Book ID
- 116357115
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 296 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0045-6535
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## Abstract The crystallization of Mefenamic Acid, (MA), which has a prevalent usage in drug formulation, was investigated. MA is a highβdose, antiβinflammatory, analgesic agent used for pain in menstrual disorders. Some negative properties of MA are a high hydrophobicity and propensity to stick to
The purpose of this study was to characterize mefenamic acid (MA) from commercial samples and samples crystallized from different solvents. Various techniques used for characterization included microscopy (hot stage microscopy, scanning electron microscopy), intrinsic dissolution rate, differential