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Environmental Factors in the First Trimester and Risk of Oral-Facial Clefts in the Offspring

✍ Scribed by Chung, M.-K.; Lao, T. T.; Ting, Y.-H.; Leung, T.-Y.; Lau, T.-K.; Wong, T.-W.

Book ID
125484120
Publisher
SAGE Publications
Year
2012
Tongue
English
Weight
273 KB
Volume
20
Category
Article
ISSN
1933-7191

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## Abstract Mutations in the gene encoding interferon regulatory factor 6 (__IRF6)__ underlie a common form of syndromic clefting known as Van der Woude syndrome. Lip pits and missing teeth are the only additional features distinguishing the syndrome from isolated clefts. Van der Woude syndrome, th