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Environmental Endocrine Disruptors Promote Adipogenesis in the 3T3-L1 Cell Line through Glucocorticoid Receptor Activation

✍ Scribed by Robert M. Sargis; Daniel N. Johnson; Rashikh A. Choudhury; Matthew J. Brady

Book ID
109969847
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
162 KB
Volume
18
Category
Article
ISSN
1930-7381

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## Abstract The androgen receptor (AR) is a ligand‐dependent transcription factor belonging to the steroid hormone receptor superfamily. Under normal conditions, in the absence of a ligand, the AR is localized to the cytoplasm and is actively transported into the nucleus upon binding of androgens.