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Environmental and occupational biomonitoring using the Comet assay

✍ Scribed by Mahara Valverde; Emilio Rojas


Book ID
116760278
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
310 KB
Volume
681
Category
Article
ISSN
1383-5742

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The comet assay (single-cell gel electrophoresis), which measures DNA strand breaks at the level of single cells, is very easily applied to human lymphocytes, and therefore lends itself to human biomonitoring studies. For the examination of DNA base oxidation (a specific marker of oxidative damage),