Environment-sensitive hydrogels for drug delivery
β Scribed by Qiu, Yong; Park, Kinam
- Book ID
- 120014560
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 864 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0169-409X
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π SIMILAR VOLUMES
Environmentally sensitive hydrogels have enormous potential in various applications. Some environmental variables, such as low pH and elevated temperatures, are found in the body. For this reason, either pH-sensitive and/or temperature-sensitive hydrogels can be used for site-specific controlled dru
## Abstract In this study, a KRGDKK (LysβArgβGlyβAspβLysβLys) peptide with a RGD sequence is utilized as a functional group to synthesize a novel thermoβsensitive hydrogel. The KRGDKK peptide prepared by a solid phase synthesis approach is coupled to the ends of a poly[(__Ξ΅__βcaprolactone)β__co__βl