Environment-dependent conformation and antimicrobial activity of a gramicidin S analog containing leucine and lysine residues
β Scribed by Shin Ono; Sannamu Lee; Yasushi Kodera; Haruhiko Aoyagi; Michinori Waki; Tetsuo Kato; Nobuo Izumiya
- Book ID
- 115919564
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 237 KB
- Volume
- 220
- Category
- Article
- ISSN
- 0014-5793
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## Abstract In order to study the role of Dβamino acid residues in keeping the stable Ξ²βsheet conformation and in the antimicrobial activity of gramicidin S (GS), the four analogs of GS containing DβAla, LβAla, Gly, and Aib (Ξ±βaminoisobutyric acid) in place of DβPhe were synthesized. DβAlaβand Glyβ
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