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Entry of elemental arsenic into the central nervous system in patients with acute promyelocytic leukemia during arsenic trioxide treatment

✍ Scribed by Wing-Yan Au; Sidney Tam; Yok-Lam Kwong


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
70 KB
Volume
32
Category
Article
ISSN
0145-2126

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## Abstract ## BACKGROUND Approximately 20–30% of patients with acute promyelocytic leukemia (APL) who are treated with all‐__trans__ retinoic acid (ATRA) and an anthracycline develop recurrent disease. It has been reported that arsenic trioxide (As~2~O~3~) is effective in this setting. The author