Entropic interaction chromatography: Separating proteins on the basis of size using end-grafted polymer brushes

The influence of grafted polymer archite

The influence of grafted polymer architecture and fluid hydrodynamics on protein separation by entropic interaction chromatography

✍ Bryan R. Coad; Bradley M. Steels; Jayachandran N. Kizhakkedathu; Donald E. Brook 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 266 KB 👁 2 views

## Abstract Entropic interaction chromatography (EIC) provides efficient size‐based separation of protein mixtures through the entropy change associated with solute partitioning into a layer of hydrophilic homopolymer that has been end‐grafted within the pores of a macroporous chromatography suppor