Enthalpy of Mixing Glycosaminoglycans with Aqueous NaCl

✍ Scribed by Robert L. Cleland

• Book ID: 102763946
• Publisher: Wiley (John Wiley & Sons)
• Year: 1979
• Tongue: English
• Weight: 535 KB
• Volume: 18
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1979.360181104

✦ Synopsis

Abstract

Calorimetric measurements of Δ__H__, the enthalpy of mixing with NaCl solutions per mole of polymer charge equivalent, have been made for the sodium salts of hyaluronate, chondroitin 4‐sulfate, and chondroitin over the range m~s~^f^ = 0–0.5 (where m~s~^f^ is final NaCl molality); corrections were made for the enthalpy of dilution of NaCl. Values of Δ__H__ for the range m~s~^f^ = 0–0.1 agree reasonably well with a theoretical estimate from the infinite line charge theory of polyelectrolytes. In order to apply the latter, calculations of several average short‐range atomic spacings in hyaluronate were made from a statistical model with use of energy parameters which provide a good fit to experimental values of unperturbed dimensions.