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Enthalpic and Entropic Effects of Salt and Polyol Osmolytes on Site-Specific Protein−DNA Association: The Integrase Tn916−DNA Complex †

✍ Scribed by Milev, Stoyan; Bosshard, Hans Rudolf; Jelesarov, Ilian


Book ID
121351959
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
106 KB
Volume
44
Category
Article
ISSN
0006-2960

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## Abstract The N‐terminal domain of the Tn916 integrase protein (INT‐DBD) is responsible for DNA binding in the process of strand cleavage and joining reactions required for transposition of the Tn916 conjugative transposon. Site‐specific association is facilitated by numerous protein–DNA contacts