Enlarged tracheoesophageal puncture after total laryngectomy: A systematic review and meta-analysis

✍ Scribed by Katherine A. Hutcheson; Jan S. Lewin; Erich M. Sturgis; Asha Kapadia; Jan Risser

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 164 KB
• Volume: 33
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.21399

✦ Synopsis

Abstract

Background

Enlargement of the tracheoesophageal puncture (TEP) is a challenging complication after laryngectomy with TEP. We sought to estimate the rate of enlarged puncture, associated pneumonia rates, potential risk factors, and conservative treatments excluding complete surgical TEP closure.

Methods

A systematic review was conducted (1978–2008). A summary risk estimate was calculated using a random‐effects meta‐analysis model.

Results

Twenty‐seven peer‐reviewed manuscripts were included. The rate of enlarged puncture and/or leakage around the prosthesis was reported in 23 articles (range, 1% to 29%; summary risk estimate, 7.2%; 95% confidence interval [CI], 4.8% to 9.6%). Temporary removal of the prosthesis and TEP‐site injections were the most commonly reported conservative treatments. Prosthetic diameter (p = .076) and timing of TEP (p = .297) were analyzed as risk factors; however, radiotherapy variables were inconsistently reported.

Conclusion

The overall risk of enlarged puncture seems relatively low, but it remains a rehabilitative challenge. Future research should clearly establish risk factors for enlarged puncture and optimal conservative management. © 2010 Wiley Periodicals, Inc. Head Neck, 2011