Enhancive Synthesis of -lβ, 11-Diol-4-en-eudesmol
✍ Scribed by Jin-Chun Chen; Guo-Jun Zheng; Chen Zhang; Li-Jing Fang; Yu-Lin Li
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 261 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0256-7660
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AbstractÐAn ef®cient synthesis has been developed affording 11b-(4-aminophenyl)spiro[estr-4-ene-17b,2 H (5 H H)-furan]-3,5 H -dione (2), main metabolite of antiprogestin (Z)-11b-[4-(dimethylamino)phenyl]-17b-hydroxy-17a-(3-hydroxyprop-1-enyl)estr-4-en-3-one (1), in an overall yield of 21%.
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