Enhancing the translational initiation frequency of a gene
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 99 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0020-711X
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A total of 405 unique single base-pair substitutions, located within the ATG translation initiation codons (TICs) of 255 different genes, and reported to cause human genetic disease, were retrieved from the Human Gene Mutation Database (HGMD). Although these lesions comprised only 0.7% of coding seq
Eukaryotic translation initiation factors and their corresponding genes have been characterized using biochemical and genetic methods from a variety of different organisms. The designations of the factors relate to their apparent roles in the biochemical process. Many gene names indicate genetic int
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Bovine mitochondrial translational initiation factor 2 (IF-2 mt ) is organized into four domains, an N-terminal domain, a central G-domain and two C-terminal domains. These domains correspond to domains III -VI in the six-domain model of Escherichia coli IF-2. Variants in IF-2 mt were prepared and t