Guanidination of the e e-amino group of lysine-terminated tryptic peptides can be accomplished selectively in one step with O-methylisourea hydrogen sulfate. This reaction converts lysine residues into more basic homoarginine residues. It also protects the e e-amino groups against unwanted reaction
Enhancing the intensities of lysine-terminated tryptic peptide ions in matrix-assisted laser desorption/ionization mass spectrometry
โ Scribed by Richard L. Beardsley; Jonathan A. Karty; James P. Reilly
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 86 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0951-4198
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