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Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants

✍ Scribed by Madi, Lea; Rosenberg-Haggen, Bianca; Nyska, Abraham; Korenstein, Rafi


Book ID
119828565
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
737 KB
Volume
22
Category
Article
ISSN
0906-6705

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## Abstract Incubation of cultured B‐16 melanoma cells with 1‐methyl‐3‐isobutyl xanthine (MIX) produced a sustained rise in intracellular adenosine 3β€²,5′‐cyclic monophosphate (cAMP) which preceded an increase in the specific activity of tyrosinase (EC 1.10.3.1). Cultures of two clones of melanoma c