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Enhancing penicillin fermentations by increased oxygen solubility through the addition of n-hexadecane

โœ Scribed by Chester S. Ho; Lu-Kwang Ju; Raymond F. Baddour


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
752 KB
Volume
36
Category
Article
ISSN
0006-3592

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Improvement of antibiotic production by
โœ Murat Elibol ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 128 KB

## Abstract A perfluorocarbon (PFC), namely perfluorodecalin, was added to fermentation medium to increase the medium's oxygen solubility. The antibiotic concentration obtained in the absence of PFC was 45โ€‰mgโ€‰dm^โˆ’3^, whereas it was 90โ€‰mgโ€‰dm^โˆ’3^ in the presence of 10% (v/v) PFC. On the other hand, b