An alternative analytical method for the determination of 15-deoxyspergualin in plasma is described. The drug was initially separated from the plasma matrix by ultrafiltration and a precolumn derivatization step was performed with naphthalene-2,3-dicarboxaldehyde in the presence of sodium cyanide to
โฆ LIBER โฆ
Enhancing Fluorescence LC Analysis of Biogenic Amines in Fish Tissues by Precolumn Derivatization with Naphthalene-2,3-dicarboxaldehyde
โ Scribed by Zotou, Anastasia; Notou, Maria
- Book ID
- 111960659
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- English
- Weight
- 267 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1936-9751
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An extremely sensitive fluorimetric HPLC method used to determine in vivo cerebral \(\alpha\)-ketoisocaproic acid (KIC) concentration with less than \(2 \mathrm{~g}\) of tissue (e.g., a single rat brain, \(\sim 1.8 \mathrm{~g}\) ) is reported. Removal of unwanted lipids and amino acids and isolation