Enhancing fluidity of concentrated antacid suspensions

✍ Scribed by Allen Heyd; Dadi J. Dhabhar

• Publisher: John Wiley and Sons
• Year: 1975
• Tongue: English
• Weight: 307 KB
• Volume: 64
• Category: Article
• ISSN: 0022-3549
• DOI: 10.1002/jps.2600641025

✦ Synopsis

Highly concentrated antacid suspensions can be fluidized by adding a colloidal polyelectrolyte to alter the charge on antacid particles from positive to negative. A deflocculated state is assumed to exist in such preparations, as supported by electrophoretic and viscometric analyses. When viscosity is directly correlated with the {-potential, viscometry becomes particularly useful in confirming that the suspension has been maximally fluidized.

Keyphrases Antacid suspensions, concentrated-fluidized by addition of colloidal polyelectrolyte, viscosity correlated with {-PO- tential, electrophoretic and viscometric measurements I I Fluidized antacid suspensions-preparation using colloidal polyelectrolyte, viscosity correlated with {-potential, electrophoretic and viscometric measurements