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Enhancing effect of wortmannin on muscarinic stimulation of phospholipase d in rat pheochromocytoma PC12 cells

✍ Scribed by Hiroyuki Kanoh; Hidenari Ohbayashi; Yuzuru Matsuda; Yoshiaki Nonomura; Yoshinori Nozawa

Book ID: 115765127
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 447 KB
Volume: 188
Category: Article
ISSN: 0006-291X
DOI: 10.1016/0006-291x(92)91085-5

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## Background: Suramin inhibits growth of neural crest-derived cells and is used to treat adrenocortical cancer and neuroblastoma in clinical trials. the antiproliferative effect of suramin was evaluated in primary cultures of human pheochromocytoma and the pc12 rat pheochromocytoma cell line in vi