𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enhancing cell growth and antibody production in CHO cells by siRNA knockdown of novel target genes

✍ Scribed by Klausing, Sandra; Krämer, Oliver; Noll, Thomas

Book ID
121591552
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
401 KB
Volume
7
Category
Article
ISSN
1753-6561

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Enhancement of monoclonal antibody produ
Enhancement of monoclonal antibody productivity by promoting active hypothermic growth in hybridoma cells
✍ Sun Li Chong; Duen Gang Mou; Saw Hoon Lim; Abdul Manaf Ali; Beng Ti Tey 📂 Article 📅 2009 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 135 KB

## Abstract **BACKGROUND:** Many reports have suggested that mild hypothermic culture conditions improve the specific monoclonal antibody (mAb) productivity of mammalian cells. The effect of active hypothermic growth on the mAb productivity of the hybridoma C~2~E~7~ was investigated. Hybridoma grow

Uncoupling of cell growth and proliferat
Uncoupling of cell growth and proliferation results in enhancement of productivity in p21CIP1-arrested CHO cells
✍ Jing-Xiu Bi; John Shuttleworth; Mohamed Al-Rubeai 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 601 KB

## Abstract Chinese hamster ovary cells have been engineered to inducibly over‐express the p21^CIP1^ cyclin‐dependent kinase inhibitor, to achieve cell cycle arrest and increase cell productivity. In p21^CIP1^‐arrested cells production of antibody from a stably integrated lgG4 gene, was enhanced ap