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Enhancer-independent promoter activity of the mouse αB-crystallin/small heat shock protein gene in the lens and cornea of transgenic mice

✍ Scribed by Rashmi Gopal-Srivastava; W.Todd Kays; Joram Piatigorsky


Book ID
118603443
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
598 KB
Volume
92
Category
Article
ISSN
0925-4773

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There are two tandemly linked dcrystallin genes (58 d1-d2 38) in the chicken, with the d1-crystallin gene being expressed much more highly (50-100-fold) in the embryonic lens than the d2crystallin gene. Previous transfection experiments have shown that a lens-preferred enhancer exists in the third i