Enhancement of urinary bladder carcinogenesis in nullizygous p53-deficient mice by N-butyl-N-(4-hydroxybutyl)nitrosamine
โ Scribed by Shinji Yamamoto; Wei Min; Chyi Chia R. Lee; Elsayed I. Salim; Hideki Wanibuchi; Tokuo Sukata; Shoji Fukushima
- Book ID
- 117469267
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 551 KB
- Volume
- 135
- Category
- Article
- ISSN
- 0304-3835
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The modifying effects of dietary administration of 1,4-phenylene diisothiocyanate (DITC) on N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced urinary bladder carcinogenesis during the initiation and post-initiation phases were examined in male ICR mice. Five-week-old animals were divided into 5 g