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Enhancement of tumor immunotherapy by deletion of the A2Aadenosine receptor

✍ Scribed by Adam T. Waickman, Angela Alme, Liana Senaldi, Paul E. Zarek, Maureen Horton, Jonathan D. Powell

Book ID
113026910
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
518 KB
Volume
61
Category
Article
ISSN
0340-7004

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The modulation of adenosine receptor with K+(ATP) channel blocker, glibenclamide, was investigated using the radiolabeled A2A-receptor selective agonist [3H]CGS 21680. Radioligand binding studies in bovine brain striatal membranes (BBM) indicated that unlabeled CGS 21680 displaced the bound [3H]CGS