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Enhancement of transdermal apomorphine delivery with a diester prodrug strategy

โœ Scribed by Kuo-Sheng Liu; K.C. Sung; Saleh A. Al-Suwayeh; Ming-Chuan Ku; Chin-Chen Chu; Jhi-Joung Wang; Jia-You Fang

Book ID
118435782
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
333 KB
Volume
78
Category
Article
ISSN
0939-6411

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This investigation includes an evaluation of the percutaneous absorption of bupropion (BUP) and hydroxybupropion (BUPOH) in vitro and in vivo. In addition, a carbamate prodrug of BUPOH (But-BUPOH) was evaluated in vitro. In vitro diffusion studies were conducted in a flow-through diffusion cell syst