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Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation

โœ Scribed by J-Y. Fang; W-R. Lee; S-C. Shen; Y-P. Fang; C-H. Hu

Book ID
108667623
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
464 KB
Volume
151
Category
Article
ISSN
0007-0963

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Topical delivery of methotrexate via skin pretreated with physical enhancement techniques: low-fluence erbium:YAG laser and electroporation
โœ Woan-Ruoh Lee; Shin-Chuan Shen; Chia-Lang Fang; Rou-Zi Zhuo; Jia-You Fang ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 220 KB

## Abstract ## Background and Objective The high hydrophilicity and molecular weight of methotrexate (MTX) make it difficult to deliver via the skin route for treating psoriasis or rheumatoid arthritis. The objective of this study was to enhance and optimize the skin permeation of MTX using two ph