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Enhancement of the antitumor activity of ionising radiation by nimotuzumab, a humanised monoclonal antibody to the epidermal growth factor receptor, in non-small cell lung cancer cell lines of differing epidermal growth factor receptor status

✍ Scribed by Akashi, Y; Okamoto, I; Iwasa, T; Yoshida, T; Suzuki, M; Hatashita, E; Yamada, Y; Satoh, T; Fukuoka, M; Ono, K

Book ID: 109999408
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 234 KB
Volume: 98
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6604222

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## Abstract The high frequency of epidermal growth factor receptor (__EGFR__) mutations in tyrosine kinase inhibitor‐responsive non‐small‐cell lung cancer (NSCLC) cases is now well established, highlighting the predictive value of activating __EGFR__ mutations in guiding the clinical use of __EGFR_