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Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro. II: Drug, vehicle, and enhancer penetration kinetics

โœ Scribed by Mitsuhiko Hori; Howard I. Maiback; Richard H. Guy

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
451 KB
Volume
81
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Enhancement of propranolol hydrochloride
Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro: Effect of enhancer lipophilicity
โœ Mitsuhiko Hori; Susumu Satoh; Howard I. Maibach; Richard H. Guy ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 469 KB ๐Ÿ‘ 1 views

The enhancement of model hydrophilic (propranolol hydrochloride) and lipophilic (diazepam) drug penetration across rat and hairless mouse skin in vitro has been studied. Preliminary experiments established that most n-alkanes having chain lengths of between 7 and 16 promote the flux of both drugs. F