Enhancement of natural killer cell-mediated cytotoxicity by coexpression of GM-CSF/B70 in hepatoma
β Scribed by Kye-Young Kim; Mi-Ae Kang; Myeong-Jin Nam
- Book ID
- 117466838
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 312 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0304-3835
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## Abstract A variety of tumours injected into rats were found to rapidly stimulate cytotoxicity which was similar to naturallyβoccurring cytotoxicity of normal rats. Cytotoxic cells from the spleen and peritoneal cavity closely resembled NK cells in their lytic specificity and cellβsurface charact
## Abstract The __in vitro__ cytotoxicity of rat natural killer cells was augmented by the incubation of normal spleen cells with a soluble factor derived from the 24βh culture of spleen cells and various tumour cells. Cytotoxicity was augmented approximately 4β, 3β or 2βfold depending on whether t