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Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling–induced matrix metalloproteinase expression

✍ Scribed by Akihiko Hiyama; Daisuke Sakai; Makarand V. Risbud; Masahiro Tanaka; Fumiyuki Arai; Koichiro Abe; Joji Mochida


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
484 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To determine whether the fluoroquinolone antibiotic ciprofloxacin, which can cause tendon pain and rupture in a proportion of treated patients, affects the expression of matrix metalloproteinases (MMPs) in human tendon‐derived cells in culture. ## Methods Cell cultures w