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Enhancement of Ibuprofen Dissolution via Wet Granulation with β-Cyclodextrin

✍ Scribed by Ghorab, Mohamed K.; Adeyeye, Moji Christianah

Book ID
119940262
Publisher
Informa plc
Year
2001
Tongue
English
Weight
213 KB
Volume
6
Category
Article
ISSN
1083-7450

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✍ Mohamed K. Ghorab; Moji Christianah Adeyeye 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB

The objectives of this study were to evaluate the bioavailability of cogranulated and oven-dried ibuprofen (IBU) and beta-cyclodextrin (betaCD), in comparison to a physical mixture, and to examine the effect of endogenous bile on the bioavailability of the drug. In vitro dissolution studies were per