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Enhancement of glucose dependent insulin secretion in man by gastrin releasing peptide (GRP)


Book ID
123058728
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
75 KB
Volume
5
Category
Article
ISSN
0167-0115

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Modulation of gastrin-releasing peptide
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Gastrin-releasing peptide (GRP) receptors are present in pancreatic islets, though their regulation is unknown except for homologous desensitization. The modulation of binding of GRP to mouse pancreatic islets and INS-1 cells was studied. At 60 min (steady-state), total binding of [ 125 I-Tyr 15 ] G