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Enhancement of delayed hypersensitivity by depletion of suppressor T cells with cyclophosphamide in mice

✍ Scribed by MITSUOKA, AKIO; BABA, MITSUO; MORIKAWA, SHIGERU

Book ID
109699711
Publisher
Nature Publishing Group
Year
1976
Tongue
English
Weight
214 KB
Volume
262
Category
Article
ISSN
0028-0836

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## Abstract A previous study (__Eur. J. Immunol.__ 1977. __7__: 714) has shown that mice injected intravenously (i.v.) with 1 Γ— 10^9^ sheep red blood cells (SRBC) produce cells which suppress delayed‐type hypersensitivity (DTH). These suppressor cells are Ξ˜β€positive, antigen‐specific and act via a

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## Abstract The relative sensitivity to cyclophosphamide (CY) of helper T cells in antibody responses and of suppressor T cells in delayed‐type hypersensitivity (DTH) responses against sheep red blood cells (SRBC) was measured by pretreating cell suspensions __in vitro__ with the microsomally activ