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Enhancement of cyclic AMP metabolism in a B cell line by protein kinase C

✍ Scribed by Christina L. Patke; William T. Shearer

Book ID
113134552
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
684 KB
Volume
130
Category
Article
ISSN
0008-8749

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## Abstract A somatic cell genetic approach has been used to evaluate the role of cyclic AMP‐dependent protein kinase in ACTH action on adrenal steroidogenesis. A mutant clone, 8BrcAMP^r^‐1, previously was isolated from an ACTH‐sensitive adrenocortical tumor cell line (clone Y1) following mutagenes