The human colon cancer cell line Caco-2 spontaneously differentiates to an enterocyte-like cell after confluence under standard culture conditions. This is characterized by polarization of the cell monolayer with the appearance of tight junctions, a brush border membrane and expression of brushborde
β¦ LIBER β¦
Enhancement of connexin 26 expression accelerates enterocytic differentiation of human colonic Caco-2 cells
β Scribed by Morita, Hidekazu; Hoshimoto, Aihiro; Katsuno, Tatsuro; Suzuki, Yasuo; Saito, Yasushi
- Book ID
- 122757466
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 137 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0016-5085
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We previously reported that the enterocytic differentiation of human colonic Caco-2 cells correlated with down-regulation of fibronectin (FN) and laminin (LN), two extracellular matrix components interacting with cell surface integrin receptors. We now investigated whether Caco-2 cell differentiatio