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Enhancement of bone formation by drawn poly(L-lactide)

✍ Scribed by Ikada, Y. ;Shikinami, Y. ;Hara, Y. ;Tagawa, M. ;Fukada, E.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 616 KB
Volume: 30
Category: Article
ISSN: 0021-9304
DOI: 10.1002/(sici)1097-4636(199604)30:4<553::aid-jbm14>3.0.co;2-i

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✦ Synopsis

Poly(L-lactide) (PLLA) was molded into films and rods, and drawn in the longitudinal direction to endow them with piezoelectricity. The piezoelectric constants of PLLA films increased with the draw ratio and, after passing a maximum at a draw ratio around 5, decreased. PLLA samples with a draw ratio 5 underwent fibrilization. The PLLA rods were intramedullarily implanted in the cut tibiae of cats for internal fixation up to 8 weeks. Fracture healing was clearly pro-

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