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Enhancement in MALDI-TOF MS analysis of the low molecular weight human serum proteome

✍ Scribed by Christine L. Gatlin; Krista Y. White; Maureen B. Tracy; Christopher E. Wilkins; O. John Semmes; Julius O. Nyalwidhe; Richard R. Drake; Dariya I. Malyarenko


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
141 KB
Volume
46
Category
Article
ISSN
1076-5174

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Capillary electrophoresis frontal analysis was applied to 12 low molecular weight compounds including 8 drug substances displaying a range of different properties with respect to binding affinity, binding location, structure, lipophilicity, charge at physiological pH, and electrophoretic mobility. I