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Enhancement and inhibition of mitogenic action of insulin-like growth factor I by high glucose in cultured bovine retinal pericytes

✍ Scribed by Keiko Naruse; Fumihiko Sakakibara; Jiro Nakamura; Naoki Koh; Nigishi Hotta


Book ID
116018880
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
705 KB
Volume
58
Category
Article
ISSN
0024-3205

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In order to explore the possible contribution of insulin-like growth factor I to the development of diabetic nephropathy, the effect of glucose on the mitogenic and metabolic actions of insulin-like growth factor I in cultured rat glomerular mesangial cells was examined. The stimulation of [3H]-thym