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Enhancement and depression of spinal reflexes by 8-hydroxy-2-(di-n-propylamino)tetralin in the decerebrated and spinalized rabbit: involvement of 5-HT1A- and non-5-HT1A-receptors

✍ Scribed by R. W. Clarke; J. Ogilvie; A. K. Houghton


Book ID
110003211
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
344 KB
Volume
122
Category
Article
ISSN
0007-1188

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Synthesis of R-(+)- and S-(−)-8-hydroxy-
✍ M. J. Ackland; L. G. Dring; J. R. Jones; N. Gilon 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The title compounds were synthesised in 7 steps from 1,7‐dihydroxynaphthalene as follows: 1,7‐dihydroxynaphthalene was methylated and subjected to a Birch reduction to yield 8‐methoxy‐2‐tetralone. Reductive amination with sodium cyanoboro[^3^H]hydride and n‐propylamine gave 8‐methoxy‐2‐