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Enhanced yield of chromosomal aberrations in human peripheral lymphocytes in vitro using contrast media in X-irradiation

✍ Scribed by W. Hadnagy; G. Stephan; F. Kossel


Book ID
113254239
Publisher
Elsevier Science
Year
1982
Weight
238 KB
Volume
104
Category
Article
ISSN
0165-7992

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Post-treatment of mutagen-treated human peripheral lymphocytes with a single-strand specific endonuclease from Neurospora crassa leads to a significant elevation of the rate of structural chromosomal aberrations. Our results indicate that DNA double-strand breaks (DSB) are ultimate lesions for the f