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ENHANCED VDUP-1 GENE EXPRESSION BY PPARGAMMA AGONIST INDUCES APOPTOSIS IN HUMAN MACROPHAGE

✍ Scribed by Billiet, L.; Furman, C.; Larigauderie, G.; Copin, C.; Page, S.; Fruchart, J.; Brand, K.; Rouis, M.

Book ID
118636051
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
65 KB
Volume
9
Category
Article
ISSN
1567-5688

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## Abstract The fate and phenotype of lesion macrophages is regulated by cellular oxidative stress. Thioredoxin‐1 (Trx‐1) plays a major role in the regulation of cellular redox balance, with resultant effects on gene expression and cellular responses including cell growth and death. Trx‐1 activity