Receptor signals and nuclear events in C
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Karen Laky; BJ Fowlkes
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Article
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2005
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Elsevier Science
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English
β 129 KB
MHC specificity in positive selection is a major determinant in the CD4/CD8 T cell lineage decision. Previous studies support the view that quantitative differences in T cell receptor (TCR) signaling in immature CD4 + CD8 + double positive thymocytes leads to an instructive bias in CD4/CD8 T cell li