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Enhanced Replication of R5 HIV-1 Isolates in vitro by a Small-Molecule Reagent Targeting HIV-1 Protease

✍ Scribed by Wardle, Nick J.; Hudson, Harry R.; Matthews, Ray W.; Nunn, Christine M.; Vella, Cherelyn; Bligh, S. W. Annie


Book ID
120355750
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
267 KB
Volume
8
Category
Article
ISSN
1860-7179

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## Abstract Protease inhibitor (PI) therapy for the treatment of patients infected with human immunodeficiency virus is frequently associated with insulin resistance and diabetic complications. These adverse effects of PI treatment result to a large extent from their inhibition of insulin‐stimulate