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Enhanced release of itraconazole from ordered mesoporous SBA-15 silica materials

✍ Scribed by Mellaerts, Randy; Aerts, Caroline A.; Humbeeck, Jan Van; Augustijns, Patrick; den Mooter, Guy Van; Martens, Johan A.


Book ID
115473549
Publisher
Royal Society of Chemistry
Year
2007
Tongue
English
Weight
327 KB
Volume
13
Category
Article
ISSN
1359-7345

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SBA-15 ordered mesoporous material is an excellent carrier material for the poorly soluble drug molecule itraconazole. Immediate itraconazole release is obtained upon contacting the formulation with simulated biological fluid. The stability of the formulation upon storage was investigated. Samples w