Enhanced productivity of protease-sensitive heterologous proteins by disruption of multiple protease genes in the fission yeastSchizosaccharomyces pombe

The phenotypic suppression of a mutation

The phenotypic suppression of a mutation in the gene rplX for ribosomal protein L24 by mutations affecting the lon gene product for protease LA in Escherichia coli K12

✍ Nishi, Kayoko ;Schnier, Joachim 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 586 KB

A suppressor mutation of a temperature-sensitive mutant of ribosomal protein L24 (rplX19) was mapped close to the lon gene by genetic analysis and was shown to affect protease LA. The degradation and the synthesis rates of individual ribosomal proteins were determined. Proteins L24, L14, L15 and L27