Altered oral bioavailability and pharmac
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Sean X. Peng; David M. Ritchie; Martin Cousineau; Earl Danser; Robert DeWire; Ja
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Article
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2006
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John Wiley and Sons
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English
โ 149 KB
Effects of coadministration of dietary supplement biochanin A (BA) on the pharmacokinetics of three P-glycoprotein substrates, paclitaxel, digoxin, and fexofenadine, were investigated in rats. With BA coadministration, the oral bioavailability and peak plasma concentration were markedly increased by