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Enhanced Membrane Permeabilization and Antibacterial Activity of a Disulfide-Dimerized Magainin Analogue

โœ Scribed by Dempsey, Christopher E.; Ueno, Shohta; Avison, Matthew B.

Book ID
120383411
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
118 KB
Volume
42
Category
Article
ISSN
0006-2960

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Parallel and antiparallel dimers of maga
Parallel and antiparallel dimers of magainin 2: their interaction with phospholipid membrane and antibacterial activity
โœ Yasuhiro Mukai; Yuko Matsushita; Takuro Niidome; Tomomitsu Hatekeyama; Dr Haruhi ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 121 KB

## Abstract Magainin 2 (M2) forms pores by associating with several other M2 molecules in lipid membranes and shows antibacterial activity. To examine the effect of M2 dimerization on biological activity and membrane interaction, parallel and antiparallel M2 dimers were prepared from two monomeric