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Enhanced insulin secretion from engineered 3T3-L1 preadipocytes by induction of cellular differentiation

✍ Scribed by Kei Fujimoto; Takashi Sasaki; Masami Nemoto; Nozomu Nakai; Kyoko Sakai; Koichiro Yamasaki; Yoshito Hiki; Toya Ohashi; Yoshikatsu Eto; Naoko Tajima

Publisher
Springer
Year
2005
Tongue
English
Weight
284 KB
Volume
268
Category
Article
ISSN
0300-8177

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## Abstract To investigate the functional relationship between the ability of the adenovirus‐5 E1A oncogene product to transform with its ability to block adipocytic differentiation and induce apoptosis, we expressed E1A in the 3T3 L1 preadipocytic cell line. The results demonstrate a dramatic, qua