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Enhanced Hepatic Uptake of Liposomes Through Complement Activation Depending on the Size of Liposomes

✍ Scribed by Hideyoshi Harashima; Kazuya Sakata; Kouichi Funato; Hiroshi Kiwada


Book ID
110380216
Publisher
Springer US
Year
1994
Tongue
English
Weight
901 KB
Volume
11
Category
Article
ISSN
0724-8741

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In vivo evaluation of the effect of the
✍ Hideyoshi Harashima; Yuriko Ohnishi; Hiroshi Kiwada πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 2 views

In the hepatic uptake of large particles such as liposomes, a serum component called opsonin plays an important role. In this study, the 'Oldendorf method' is introduced to evaluate the hepatic extraction under the condition of single passage, which enabled examination of the effect of opsonization